The veteran striker was substituted moments before half-time during the 3-0 defeat at Southend on Friday night with a hamstring problem.
Although it was only a precautionary measure, manager Paul Cook is unlikely to risk his front man against the Minstermen unless fully fit.
The Spireites will continue to be without fellow striker Jack Lester who serves the second game of his three-match ban.
Cook will be able to call upon Luis Boa Morte again, after the Portuguese attacking midfielder showed no cause for concern on his return from a hamstring problem.
The npower League Two side saw their five-match unbeaten league run come to an abrupt halt at Roots Hall, and will be looking to bounce back in their mid-table clash against Gary Mills' side.