Both are suffering from ankle injuries and will be assessed ahead of the clash.
The Robins, who will again be managed by senior players Tommy Miller and Darren Ward, will also be without left-back Joe Devera as he closes in on a return to fitness.
Meanwhile, Luke Rooney is set to be involved again having come back in from the cold after five months out of the first team picture.
The 30-year-old has not made a senior appearance for the club since September and instead spent loan spells at Burton and Rotherham, but he was an unused substitute in Saturday's 1-1 draw with Preston.
Swindon currently sit in second place in npower League One having gone 13 games unbeaten, a run that stretches back to late November.