Matt Tootle is suspended after he was sent off during Tuesday night's penalty shoot-out triumph over Doncaster in the Johnstone's Paint Trophy at Gresty Road.
Utility man Kelvin Mellor would normally deputise but he remains sidelined with a knee injury, meaning Harry Davis or Ollie Turton could be asked to fill the void.
Elsewhere, Davis has selection issues of a more welcome nature after he shuffled his pack to good effect against Rovers.
Goalkeeper Steve Phillips, defender Adam Dugdale, midfield Brad Inman and forward Max Clayton were all handed starts and did their causes for a place in the first XI at Deepdale no harm at all.
Skipper Luke Murphy provides another option in midfield having overcome a niggling groin problem, but striker Ajay Leitch-Smith (ankle) remains on the sidelines.