Williams trained with the Shrimps over the summer and appeared to have secured a contract in October, only for international clearance issues to scupper the deal.
But the former Rhyl and Chester man has now been given the green light to join up with Jim Bentley's squad and may come into contention.
Williams' fellow midfielder Andy Fleming will be available having missed the goalless draw with Bradford on New Year's Day through illness.
Jordan Burrow is hoping to retain his place after the forward made a first start since recovering from knee ligament damage against the Bantams.
Bentley must adjust to life without striker Richard Brodie and full-back Jordan Mustoe after the pair returned to Crawley and Wigan at the end of their respective loan spells.
Supporters have been offered free entry to the match as Morecambe look to address the issue of falling attendances.