While Wilson has been on international duty, the Potters have replaced the departed Tony Pulis with Hughes, leaving him and his club-mates with a new man to impress.
He said: "It doesn't bother me in the least. That's football, isn't it? People come and go. I wish Tony all the best. He did a terrific job when he was there, but obviously we have got the new manager now and I think everyone will be trying to impress him."
Wilson added: "I haven't met Mark yet, but in the past, he's done a great job wherever he's been and I'm looking forward to working with him."
Hughes' reputation took something of a hammering after his ill-fated spell at QPR, which came to an end in November last year with the club in a tailspin which even renowned escapologist Harry Redknapp could not stop.
But Wilson is confident the Welshman's track record before his arrival at Loftus Road is a better indicator of his talents.
He said: "He's done a terrific job wherever he has been. At QPR, he could have been given a bit more time down there. But he's a guy who likes to play football and that's what I like to do anyway, so I am looking forward to it."