In a nine-man squad, the 29-year-old Russian is being tipped by his team for a top-10 finish.
"As usual it will be a long, demanding competition," said team director, Valerio Piva, "The Giro d'Italia is always one of the hardest race of the whole season, and this edition won't be any different. If you have a team with a rider that will fight for general classification, you must be focused from the beginning to the end.
"I think our team can obtain a good result: we will have Trofimov as a leader, but also Caruso proved to be really in shape so we will see. We will have also many riders that can win a stage, such as Paolini, Belkov and Brutt: we will attack and stay in the breakaways all the time we can. So, our goal will be to win at least a stage, and to take a good final position in general classification: I think Trofimov can enter the top-10, and I would be very happy if we manage to take this result."
Katusha line-up for the Giro d’Italia: Maxim Belkov, Pavel Brutt, Giampaolo Caruso, Vladimir Gusev, Petr Ignatenko, Dmitriy Kozonchuk, Luca Paolini, Yuriy Trofimov, Angel Vicioso
The event starts in Naples on Saturday and is exclusively live in the UK on British Eurosport.