He was replaced after 37 minutes by his namesake Kyriakos, before being taken to hospital where scans showed the 27-year-old had suffered damaged ligaments in his left knee.
After returning to the team hotel, the Hellenic Football Federation (EPO) issued a statement saying he would return home for treatment, UEFA.com reported on Saturday.
Greece next face the Czech Republic in Wroclaw on Tuesday after Dimitris Salpingidis's second-half goal earned a draw with Poland who had opened the scoring through Robert Lewandowski.
