Juventus-bound Llorente struck just before half-time to cancel out Bruno Gama’s 38th-minute opener.
The visitors were forced to play the final minutes with 10 men after Ander Iturraspe was dismissed.
Llorente’s only other Liga goal came in the 3-3 draw with Espanyol back in September. He has been in and out of the squad after falling out with coach Marecelo Bielsa following his decision not to extend his contract.
The result puts Depor two points clear of the relegation zone as they continue their great escape, although the bottom two – Celta Vigo and Real Zaragoza – play each other on Monday.