Home side Plabennec struck first in a shock 28-minute goal from Richard Pelletier at Stade Francis-Le Ble in Brest.
But the home crowd didn't have much to cheer about for long after Nicolas Kernevez netted an own goal only four minutes later.
Nolan Roux locked in the advantage for Lille as the visitors flexed their muscles after the break, before Tulio de Melo sealed the deal on the 67th minute.


