British wheelchair fencing champion Adrian Derbyshire suffered the break-in at his house in Warrington at 7.30am on Saturday morning.
Police have arrested three men in connection with the crime, but much of the star’s most prized equipment – including his wheelchair, swords, Paralympic torch and several gold and silver medals – have yet to be recovered.
"It's completely devastating and soul-destroying,” said the 38-year-old, who took up his sport after a brain haemorrhage four years ago.
"They've stolen my entire livelihood, they've wiped my kit out completely. It's just disgusting. This could be the end of my career. I can't compete or train anymore."
Derbyshire added that the thieves had the sole intention of stealing his specialist gear, which included coaching aids used for teaching his sport to disabled children.
"Without these specialist items I could be forced to retire from the Great Britain fencing squad,” he added.
Derbyshire is the star of the British team and had high hopes of winning a medal at London 2012, but injury forced him to pull out of the Games just weeks before the event began.
Anyone with information should contact Warrington CID on 101 quoting incident number 205 or call Crimestoppers on 0800 555 111.