Joe Schmidt's charges started the game with the clear intention of attacking their visitors from the word go and following some excellent early pressure in the Italians' half, they were rewarded with a 10th-minute try.
The industrious Ryan reached over in the corner at the end of a long spell of play on the right wing. Ian Madigan was off target with a difficult conversion attempt.
The home supporters only had to wait three more minutes for their side's next try, as hooker Sean Cronin ran through on the left side following a couple of outstanding breaks by his Ireland colleagues Luke Fitzgerald and Fergus McFadden.
Madigan had no problem adding the extras on this occasion.
After Treviso fly-half James Ambrosini missed a decent opportunity from a close-range penalty in the 17th minute, Leinster increased the cushion to 19 points with Ryan's second try - the product of a well orchestrated lineout drive.
Cronin joined him in bagging a brace when he finished off a sweeping move in front of the posts just four minutes later, securing the bonus point in the process.
Centre Andrew Goodman, who had an excellent 54-minute shift, stormed into the 22 and Cronin took a superb angle to gather the pass and scorch through.
Madigan was on hand to convert both of scores.
Treviso pressed towards the end of the first half but Leinster held onto a seemingly insurmountable 26-0 lead at the interval.
When the sides met in Treviso in September, Leinster emerged as 19-18 victors after a titanic struggle. They needed a late drop goal from the currently injured Jonathan Sexton to seal the victory.
This rematch was a completely different affair with Leinster maintaining their momentum into the second period.
The 22-year-old Ryan showed initiative to break away from a maul before touching down to complete his hat-trick.
Madigan's radar was very much in check for this tie, and he superbly converted from the left touchline to bring his personal tally up to eight points.
Credit must go to Treviso, however, as they displayed a willingness to achieve some sort of a consolation from their trip to Dublin.
Franco Smith's men got the score that their efforts deserved when winger Ludovico Nitoglia showed plenty of sharpness to ground the ball on the right at the end of a fine team move.
Schmidt introduced a number of familiar faces from the replacements bench, including regular captain Leo Cullen.
Treviso continued to enjoy some promising spells of possession in the Leinster half, but a fifth and final try soon followed for the province.
Leo Auva'a, a late call-up to the replacements bench, got over to the right of the posts.
With Madigan now off the pitch it was left to McFadden to comfortably convert, wrapping up a pleasing night for the hosts who were captained by young flanker Rhys Ruddock on the occasion of his 50th cap.
In the night's other RaboDirect Pro12 clash, fly-half Owen Williams kicked all Scarlets' points as the region celebrated a double over Munster with a 18-10 victory at Parc y Scarlets.
Veteran Ronan O'Gara only managed one penalty from four attempts for the visitors, although he did convert wing Denis Hurley's late consolation try.
Both sides had Six Nations squad members in their line-ups. Munster were boosted by the inclusion of Donncha O'Callaghan and O'Gara, while the Scarlets included Josh Turnbull and Liam Williams.
O'Gara had a testing early kick after the Scarlets were penalised on halfway, but he left his effort hanging short of the target.
It was not a great start for the fly-half and things did not improve. The Scarlets were caught offside in front of their posts, but again O'Gara failed with his kick from 35 metres out, the ball rebounding off the left upright.
While O'Gara struggled to find his range' his opposite number Owen Williams opened the scoring with a sweetly struck penalty on 14 minutes.
Owen Williams was short with another attempt inside his half, but back on target with his third shot on 18 minutes to double the Scarlets' lead.
Eventually Munster got a foothold in Scarlets territory, with O'Gara finally on target with a 29th-minute penalty from 25 metres out after the home side were penalised at a scrum.
But that was cancelled out by the in-form Owen Williams, who kicked a fine 55-metre penalty to give the Scarlets a 9-3 interval lead.
Munster's discipline let them down at the start of the second half with wing Johne Murphy conceding a penalty for a clash with Phil John, but fortunately for the Irish side Owen Williams was off target with his penalty kick.
But Munster still continued to struggle. Owen Williams kicked his fourth penalty, while O'Gara missed his third from four attempts.
It got even worse for the Irish as captain Mike Sherry was sin-binned on 56 minutes, allowing Owen Williams to kick a fifth penalty as Scarlets led 15-3.