Last weekend's home draw with Hull FC was played in such bad conditions that their usual field was deemed unfit for their Easter clash with Catalan Dragons, which was switched to Esher.
And, with the Stoop still struggling to recover, the club have announced that next weekend's meeting with Bradford, originally scheduled for Friday, has been moved to Saturday and Wycombe's Adams Park ground.
With Harlequins set for a Heineken Cup quarter-final at the Stoop next Sunday, the decision has been taken to preserve the pitch as much as possible.
"Since the Hull FC game we have been working tirelessly to find alternative venues for the Catalan and Bradford games. We have looked at all options including postponement and reversing the fixture, but this is the only option we have," said London CEO Gus Mackay.
"We appreciate our fans inconvenience with the venue changes for the last two games and we are working to ensure this sort of situation doesn't arise in the future.
"The pitch situation is something that is out of our control and we have been working with the RFL and Harlequins RU to source an alternative venue since last Monday night. We have been reluctant to postpone these fixtures and cause a fixture backlog later in the season."
The Bradford fixture will kick-off at 3pm.