The Rhinos are without the club's seven England internationals as well as a rested Jamie Peacock, but Leeds fans will have a chance to see new signings Joel Moon, Joe Vickery and Mitch Achurch in action for the first time.
Moon and Achurch have joined the champions from Salford and Penrith Panthers respectively while fellow Australian Vickery is hoping to earn a contract during a three-month trial.
The Rhinos are without Stevie Ward and Richard Moore, who are still recovering from injury, but coach Brian McDermott includes hooker Paul McShane, who has returned from his loan spell at Widnes to line up alongside Grand Final winners Ben Jones-Bishop, Danny McGuire, Ryan Bailey, Ian Kirke and Darrell Griffin.
Wakefield will give a debut to high-profile Australian signing Justin Poore, while coach Richard Agar also includes fellow recruits Reece Lyne and Bobbie Goulding in his initial squad.
Goulding is the son of former St Helens and Great Britain scrum-half Bobbie Goulding who has joined the Wildcats from Warrington's academy team.
Widnes will take a look at trialists Phil Joseph and Matty Sarsfield in their Boxing Day friendly against Warrington at the Stobart Stadium.
Former Huddersfield and Swinton forward Joseph made six appearances in Super League for Bradford in 2012 before being released while ex-Wigan academy second rower Sarsfield was recently released by Huddersfield.
Warrington include prop forward Paul Wood for his first appearance since rupturing a testicle in his side's Old Trafford defeat by Leeds in October.
He is one of seven Grand Finalists set for a run-out, while half-back Gareth O'Brien makes his return from a shoulder injury.