Yarde started in the November opener against Australia, but a hip injury then sidelined him for the Twickenham appointments with Argentina and New Zealand.
Yarde's Irish team-mate and fellow wing Topsy Ojo, though, believes his colleague will now channel that disappointment into domestic matters.
"It was disappointing for Marland," Ojo said, ahead of Saturday's Premiership trip to Leicester. "He had a good outing in his first game (of the autumn) and he was looking to carry that on.
"I think with the game against New Zealand, it just goes to show that if you are not 100 per cent it is a massive risk to play when you are not fully fit, and the coaches were not prepared to take that.
"But he will be looking to channel that disappointment at missing out into putting in some big performances for London Irish.
"We've got six or seven weeks now of rugby, and he will be thinking 'let me go back to what I was doing', which was playing well and scoring tries.
"You always want to play in an England shirt. I'm happy he got that first run-out of the autumn but obviously gutted that he didn't get more time to enhance his reputation.
"But the coaches would have got a good look at him. He will still be involved in the Six Nations and I think long-term, playing week in, week out for London Irish, he will be in with a shot for the 2015 World Cup."
Elsewhere on Saturday, Exeter host Saracens, Gloucester travel to Harlequins and Northampton entertain Newcastle, but the Premiership action starts on Friday night when Sale Sharks meet visitors Worcester.
And Worcester boss Dean Ryan believes this season's LV= Cup campaign has lifted the Warriors as they prepare to resume league action from a position of nine points adrift at the basement.
Ryan's men gained their first victory of the season when they defeated Cardiff Blues a fortnight ago, which came after seven successive Premiership defeats and a winless start to their Amlin Challenge Cup pool.
"The LV= Cup has been a real shot in the arm for us," Worcester rugby director Ryan said.
"I've been pleased with the attitude, enthusiasm and energy of our youngsters, and it has created a nice vibe around the team.
"Professional rugby is about a conveyor belt where youngsters are pushing the senior guys.
"In the past we've had the nature of being quite senior and keeping places static, and one of the key challenges is to try and change that.
"Now we have to see whether these senior guys can respond. If they don't step up to the challenge, they know there are some very talented youngsters behind them."