His is one of four changes to the pack as Glasgow pair Ryan Grant and Tim Swinson return for the final Autumn international alongside Montpellier's Johnnie Beattie, with Alasdair Dickinson, Richie Gray, Alasdair Strokosch and John Barclay dropping out.
In the backs, winger Tommy Seymour is provisionally included but a leg injury may yet rule him out.
Scotland will hope to bounce back after last week's 28-0 humiliation at the hands of South Africa against a Wallabies side missing five players suspended after they were involved in a late-night drinking session.
The match is also a landmark for lock Jim Hamilton who will become the 35th Scot to win 50 or more caps for his country.
One of Hamilton's predecessors in that distinguished club, Sean Lamont, would equal Gregor Townsend as the third most-capped Scotland back should he win his 82nd cap on Saturday.
And in a further statistical nicety Johnnie Beattie will overtake his dad, John, when he wins his 26th cap, Beattie senior having won 25.
Scotland head coach Scott Johnson said: "A six day turn-around from one Test match to another is always a challenge and it's one we'll face in our opening two games of the 2014 RBS 6 Nations Championship too.
"Tommy Seymour took a bang on the leg against South Africa at the weekend so we're looking to give him every opportunity to prove his fitness. We'll finalise our starting back division and bench once we have an update there.
"We're clear in what we're trying to do at the moment which is look at different combinations with a view to intensifying the competition for places in the team. That mantra doesn't change, so we adhere to the plan, while dealing with injuries and while always being true to the jersey.
"Australia played some quality rugby against Ireland last weekend and we're very much looking forward to renewing rivalry with them on Saturday."
Johnson has selected 11 backs for the matchday squad but will not name the starting seven until a later point.