Wade was at the heart of a thrilling attacking performance and he had a hand in the three first-half tries, scored by David Strettle, Billy Twelvetrees and Ben Morgan.
The Wasps wing did not score himself but his all-round contribution impressed head coach Stuart Lancaster, who said: "Christian did what he does in the Premiership. He sets our attack alight and he causes problems in defence."
When Lancaster addressed England's debutants at the traditional pre-match shirt presentation, he told them to consider those who had worn the shirt before and to do it justice.
Wade said: "He spoke about three things. (He asked) what does it mean to get the shirt? And to think about the guys who have worn the shirt before you - so for me players like Jason Robinson, Mark Cueto and Paul Sackey and stuff - so you have to look at those things.
"He also spoke about what are you are going to do to kind of fulfil the shirt as well. I thought I had a good game. We've been advised to look up and to play what we see and make a decision and go with it.
"With the way we play there is the opportunity for wingers to go hunting for the ball. You get the chance to play off nine and 10, to come off my wing to look for work. It was a great game and great to finish with a win."
Matt Kvesic also made his Test debut from the start on Saturday and he impressed at openside flanker, helping England secure the quick ball with which they attacked Argentina. The Pumas dominated posession the second half and England were resiliant in defence to keep them out, although Courtney Lawes was sin-binned and Lancaster has demanded greater discipline next weekend.
"I was speaking to Mike Brown who is my roomie and kind of my mentor on this tour. He was saying that the difference between Test and club level is that you can't switch off," Wade said.
"Every single play and every single phase is that you need to be on the ball. I think at half-time we knew what we had to do but Argentina, all credit to them, stepped it up and showed what a tough team they are to beat."