The Biancocelesti have been strongly linked with the Argentine who has asked his current Belgian side for a move away.
“His transfer will be made official once Biglia has completed his international commitments with Argentina,” President Roger Vanden Stock noted.
The 27-year-old will cost Claudio Lotito’s club an initial transfer fee of around €5million (£4.25m). That could increase if certain bonus clauses are activated.
The midfielder is set to sign a four-year deal in Italy.