The team manager, whose side drew 13-13 in Dublin last weekend, has brought in the uncapped Alexandre Flanquart to make up the numbers at training after lock Yoann Maestri suffered a minor shoulder problem against the Irish.
"Yoann is doubtful until Thursday but we hope he will be 100 percent fit this weekend," Saint-Andre said in a statement.
"On Friday we will make a decision on Yoann, but whatever happens Alexandre will have worked with us all week."
France surprisingly sit last in the standings with one point.
Scotland are third with four points and Italy, who next host Ireland in their final game, lie fourth on two.