The American made amends for the controversy of the opening race of the season in Calgary, when she again edged Yarnold into second, only to be disqualified for an equipment infringement, a decision she claimed left her 'heartbroken'.
But Pikus-Pace set a different pace to her rivals, finishing 0.68 seconds quicker than Yarnold across two runs while Canada's Sarah Reid completed the podium.
British world champion Shelley Rudman secured another top five finish, improving last week's fifth to rank fourth, and Donna Creighton was 2.65 secs off the pace in 21st.
After his third place in the opening World Cup in Calgary, Great Britain's Dominic Parsons settled for a top ten ranking.
His combined time across two runs was 0.87 secs slower than Russian winner Alexander Tretiakov, while Latvia's Martins Dukurs and American Matthew Antoine took second and third.
Britain's Kristan Bromley finished 17th while Ed Smith's start line difficulties meant he ranked 26th and failed to make the second run for the second consecutive week.
© Sportsbeat 2013