The 23-year-old, who added the world 500m title to her Olympic gold medal over the same distance in Heerenveen last year, stormed to victory in the first 500m race on day one.
And she was not to be denied on day two either even extending her winning margin over American Heather Richardson to more than two tenths of a second having beaten her by a tenth in race one.
Lee clocked 37.92seconds, seven tenths slower than on day one, for victory while Richardson held off Olympic silver medallist Jenny Wolf by one hundredth of a second for a second runners-up spot.
Meanwhile Canada's Christine Nesbitt, the reigning Olympic champion over 1000m, upset the home crowd by edging out two Dutch skaters to win the first ladies' 1500m race of the season.
The 27-year-old recorded a winning time of 1:56.35minutes with Marrit Leenstra second in 1:56.42 and teammate Lotte van Beek a further second back in third.
In the first of two men's 500m races in Heerenveen, Pekka Koskela beat Poland's Artur Was by two hundredths of a second with a time of 34.96 with another Dutch skater, Jan Smeekens, third.
Smeekens' teammate Kjeld Nuis finished in the same position in the men's 1000m race as Koskela this time had to settle for second just behind Canadian Denny Morrison.
There was something for the home crowd to cheer about in the men's team pursuit as the Dutch trio of Jan Blokhuijsen, Sven Kramer and Koen Verweij took victory.
They finished over three seconds ahead of the Russian trio of Yevgeny Lalenkov, Ivan Skobrev and Dennis Yuskov in 3:39.76 with Korea not far behind in third.
And there was another Dutch winner in the ladies' mass start as Mariska Huisman edged out compatriot Jorien ter Mors by one hundredth of a second to win in 8:22.96.