With the two automatic places already claimed by Juventus and Milan, there is one qualification spot up for grabs.
Udinese leapfrogged Napoli into third after they beat nine-man Genoa 2-0 thanks to goals from Antonio Di Natale and Antonio Floro Flores.
Alessandro Diamanti and Matteo Rubin struck for Bologna to beat Napoli 2-0 and send them down to fifth.
Their misery was compounded when Blerim Dzemaili saw red minutes before the full-time whistle.
Fourth-placed Lazio are now two points behind Udinese - and one ahead of Lazio - after Libor Kozak and Lorik Cana notched away at Atalanta to give them a 2-0 victory.
In a topsy-turvy eight-goal thriller at Stadio Renzo Barbera, Fabrizio Miccoli bagged a hat-trick as Palmero drew 4-4 with Chievo.
The relegated pairing of Novara and Cesena met at the Stadio Silva Piola and it was the home side who claimed the spoils as Marco Rigoni netted a treble to secure a 3-0 win.
Earlier in the day Parma picked up three points at Siena, another 2-0 scoreline, with goals from Sebastian Giovinco and Sergio Floccari.
Inter Milan could finish as high as fourth after a 4-2 victory over AC in the Milan derby - a result that also helped Juventus win the league.