Jan Vertonghen insists Tottenham are more than capable of ending their 23-year wait for a victory at Old Trafford.
Tottenham's record - they have only taken four points on trips to face the Red Devils since Gary Lineker scored in their last win in 1989 - makes them big underdogs for the clash, but Vertonghen insists the Londoners can pull off an upset.
"We are strong enough to beat them," Vertonghen said. "We have a good team, we've won the last two or three games now playing good football and everyone is hopeful of getting a good result at Old Trafford."
Vertonghen knows what it is like to taste victory at Old Trafford having won there last year in the Europa League with Ajax.
And with Spurs now seemingly finding their rhythm under new boss Andre Villas-Boas, the Belgian is hopeful about his team's chances of putting their Old Trafford hoodoo to bed.
"When I played against them last year they beat us in the Amsterdam Arena 2-0 and I think they thought they could beat us at 60 per cent," he added.
"It was a good game at Old Trafford. We beat them in the last minute and that showed that with good counter-attacks you can win there."
Although Wednesday's win at npower League One side Carlisle will hardly stand among Villas-Boas' best achievements in management, it did maintain the momentum that has built up in the last two weeks at White Hart Lane.
A rocky first half against QPR aside, Spurs have looked much better recently.
"If we win we can get up towards fourth or fifth place," Vertonghen, 25, said. "Maybe Chelsea are the strongest team with the biggest squad but look at Arsenal, look at us, everybody can win."