St Helens caretaker coach Mike Rush admitted his side would have to wait for news on the fitness of Tony Puletua and Ade Gardner after both were forced off in the 18-12 victory over Castleford Tigers.
Puletua made an early exit holding his left arm, while Gardner was carried off on a stretcher after an aerial contest with Josh Griffin.
"It's probably too early to get a full diagnosis," Rush said. "Obviously TP has got a shoulder injury and with Ade we're not sure yet to be honest."
Saints also lost Gary Wheeler in the second half, although Rush appeared less concerned by the nature of the 22-year-old's injury.
"Gary just pulled up - I'm not sure whether it's his hamstring," he added. "I'm not sure how bad it is, it could be something or nothing really."
Tigers coach Ian Millward was understandably heartened by his side's efforts in the absence of several of their leading stars.
"It was very, very close. I'm very proud of the players and their attitude," he said.
"Their defence was quite outstanding today, but unfortunately we came up with a couple of errors and they picked the ball up from two of them and scored points from it.
"I don't think that was a reflection on how tough we played. We probably lacked a bit of a cutting edge down on the try line because of some of the key players we had out.
"When you take out your four key attacking players - your full-back (Richard) Owen, your two halves (Danny) Orr and Rangi Chase, and then Daryl Clark - it does have an effect. But I can't question anything about the players' performance, their attitude or their desire to win. It was very close to being a drawn-up game."