Murray crashes out in Montreal opener
The South African took the first game of the first set and never looked back with a dominant performance to end Murray’s hopes of a third straight Rogers Cup in little over an hour.
The duo had only faced off once before, with the Scot seeing off Anderson 6-1 6-1 6-2 at last year’s Australian Open, but it was an equally one-sided encounter this time with the world number 35, who will face either Stanislas Wawrinka or Michael Russell in round three, utterly dominant.
Starting as he meant to go on, Anderson began the contest with a powerful ace and swept the first game before breaking Murray’s serve for the second en route to an unexpected 3-0 lead.
The title holder played catch-up for the remainder of the set and though he was able to pull a few games back, including winning a cracking sixth game, Anderson always retained at least a two-game lead on his way to taking the first set by three, finishing in style with his third ace.
Murray began set two hesitantly and a fault-ridden performance led to the underdog breaking his serve at once and then sweeping his way to a 2-0 advantage, and while Murray took the third game, book-ended by two aces, it was downhill from there.
The fourth game of the second set was arguably the most entertaining of the contest, but Murray wasted a double break point to go 3-1 down and Anderson made it four games on the bounce to knock out his lacklustre opponent.
Utilising a great return to match his strong and consistent service, Anderson dispatched the first of two break points before edging from deuce to find himself one game away from a win that would cap what has been a career-best year thus far.
And that he did, once again against service, after the two traded exchanges up to 30-30. Murray, who received a first round bye due to his seeding, had his two-year perfect record in Montreal ended in a 69-minute massacre.
Murray was joined at the exit by Gilles Simon, the ninth seeded Frenchman going down 7-5 6-2 to Germany's Philipp Petzschner.
It was smooth passage, however, for Simon's French compatriot Richard Gasquet who blasted his way into the second round with a 6-3 6-2 demolition of German Florian Mayer.