North Wales Crusaders' inaugural Carnegie Challenge Cup tie will be against Toulouse.
The re-formed Wrexham outfit, who played their first game in Co-operative Championship One last Sunday, will host the French club in a third-round tie at the Racecourse Ground later this month.
Crusaders coach Clive Griffiths said: "I'm glad we're at home, that's the main thing. A famous club like Toulouse is certain to bring the crowds in and with fans like ours it's certain to be a big event."
Barrow will play the other French outfit, champions Lezignan, while the Royal Navy's reward for their 32-14 second-round victory over Leigh Miners Rangers is a trip to Hunslet.
Batley, the first-ever Cup winners in 1897, were paired with Workington in one of two all-Championships ties. Leigh meet London Skolars in the other.
The 14 Super League clubs enter the competition at the fourth-round stage.
The full draw, which was conducted by former Workington scrum-half Sol Roper, who twice played at Wembley for the Cumbrians in the 1950s, and ex-Whitehaven, London and England forward Rob Purdham, is:
Oulton Raiders v Sheffield Eagles; North Wales Crusaders v Toulouse; London Skolars v Leigh; Myton Warriors v Halifax; York v Hull Dockers; Gateshead v York Acorn; Hunslet Old Boys v Featherstone; Swinton v Siddal; Workington v Batley; Doncaster v Sharlston; Egremont v Oldham; Whitehaven v Hunslet Warriors; Wath Brow Hornets v South Wales Scorpions; Barrow v Lezignan; East Hull v Rochdale; Hunslet v Royal Navy; Bradford Dudley Hill v Keighley; Dewsbury v Thatto Heath.
Ties to be played on the weekend of March 24-25.