Serie A - Round-up: Aquilani rocket launches Juve
Alberto Aquilani opened the scoring with a ferocious long-range strike as Juventus cut through Lecce 4-0.
Milos Krasic was the mastermind behind the commanding Juventus display, creating three of the goals. Four Lecce players picked up bookings for poor challenges on the Serb as they struggled to contain him.
He kept his strike low and it blazed into the bottom corner.
Lecce for their part were comfortable in possession and had plenty of the ball, but failed to test Marco Storari in the Juventus goal with any regularity.
Krasic, popping up on the left, then won a penalty as he tried to skip past Andrea Rispoli after the half hour mark.
Melo tucked it away with impudence, floating the ball gently down the middle of the goal past a pre-committed Antonio Rosati.
The third came just before the interval as Krasic exchanged passes with Amauri, surged into the box and chipped across goal for Quagliarella to head home.
In the second half Juventus coasted as Lecce looked forlornly for a way back into the game.
Manager Luigi Di Canio made a double change at the interval but the closest his side came was a header from new man Edward Ofere which Storari caught cleanly.
When Juventus broke they remained dangerous - Quagliarella spurned a golden opportunity to score his second after a flowing move, and Marchisio too went close to getting on the end of a series of sharp passes.
In between these chances Krasic scythed through four men and was only one heavy touch away from a special solo goal.
He also hit the crossbar with a dipping cross as the minutes ticked away, but the fourth finally came with ten minutes remaining.
Del Piero, brought on to a hero's welcome from his home crowd, put the icing on the cake by turning past his man and lashing a shot past Rosati for his first Serie A goal of the season after Krasic's pass had released him.
Juventus go fifth to keep in touch with the leaders in Serie A, while Lecce slip further into the bottom half of the table as their spirited bid for survival continues.
Elsewhere, Napoli, fourth going into the weekend, missed the chance to join the leaders after a 1-1 draw at Catania where Edinson Cavani netted a sixth league goal.
The table is beginning to take on a familiar look and Palermo joined Juve on 11 points in fifth after Javier Pastore and Josip Ilicic enhanced their growing reputations with spectacular strikes in a 4-1 win at home to struggling Bologna.
Injury-hit Fiorentina slumped to the bottom after Antonio Cassano scored the winner in Sampdoria's 2-1 comeback victory while Cesena drew 1-1 with Parma and Udinese won 1-0 at Brescia.