It happened during a seven-on-seven drill when Maclin took a few steps off the line of scrimmage and dropped to the ground, writhing in pain.
The injury is especially bad timing for both Maclin and the Eagles. The team's first-round draft pick out of Missouri in 2009 (19th overall) is entering a contract year.
New head coach Chip Kelly was counting on him as a big part of a new, face-paced offense.
Responding to support from teammates and fans, Maclin wrote on his Twitter account @JMAC_18, "Appreciate all the love and support the twitter fam. ... sad day but I have setbacks my entire life. Minor setback for a MAJOR comeback #birdgang."
During the 2010-2011 seasons, Maclin tied New York Giants receiver Hakeem Nicks with a league-best seven red-zone touchdowns.
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Baltimore Ravens tight end Dennis Pitta suffered a dislocated hip and will miss at least six weeks, including the Ravens' opener in Denver.
The Ravens' leading returning receiver collided with safety James Ihedigbo on a jump ball in the back of the end zone, NFL.com reported. Pitta covered his face with a towel as he was carted off the field.
He caught 61 passes for 669 yards and seven touchdowns during the Ravens' Super Bowl winning season last year.
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Despite Dallas Cowboys quarterback Tony Romo looking sharp early in training camp, it is unlikely he will see action in the Hall of Fame game.
Cowboys coach Jason Garrett told 105.3 The Fan in Dallas-Fort Worth on Friday that Romo might not make even a cameo in the preseason game on Aug. 4 when the Cowboys play the Dolphins.
"It's one of those deals where I suppose he could play five plays or whatever, but we might lean to no plays," Garrett said. "But the clock starts on our (first-teamers) in Week Two of the preseason. So that's not going to be Tony's game."
Romo had offseason surgery to remove a cyst from his back, causing him to miss the offseason program and to be limited in training camp, so far.
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Houston Texans running back Arian Foster does not know when he will be able to begin practice and will not rush back from a calf strain that has landed him on the physically unable to perform list.
"You can't play through it," Foster told the Houston Chronicle. "It's not like you're playing through a broken collar bone. I've played through a lot of things, this is just something you can't. There's no reason to right now. I'm just going to take my time."
Foster was injured during organized team activities and has been rehabbing during the offseason. He can be taken off the physically unable to perform list at any time, but if he is on it after the second round of cuts, he will not be allowed to be activated for the first six weeks of the regular season.
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