Maidana knocked Broner down in the second and eighth rounds with superb left hooks to the head at the Alamodome in the 12-round contest.
The final scores from the judges read: 115-110, 116-109, 117-109.
Broner was hurt with five big hooks in the final rounds as Maidana closed out a fine win against the champion who came into the fight with a record of 27-1 and 22 knock-outs.
Referee Lawrence Cole took a point away from Maidana for a head-butt in the eighth round after a knockdown while Broner was repeatedly warned for shoving without punishment.
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