James Anderson and Stuart Broad already have their names pencilled on to the team sheet to face Australia, but there are question marks over the form of Steven Finn.
The Middlesex bowler looked low on confidence at times during the opening Test win at Trent Bridge, taking two wickets in the opening innings but conceding 24 runs in just two overs bowled on the final day of a nail-biting contest.
Finn faces pressure from Tim Bresnan and Graham Onions for a place in the line-up, although the fact the match is taking place at his home ground could work in the 24-year-old's favour.
England skipper Cook was keeping his cards close to his chest over who would take to the field.
"We'll make decisions by tomorrow morning, by the toss," he said.
"We're in a fine position at the moment in terms of fast bowling stocks. We've got a lot of very good fast bowlers and it's always a tough call.
"Your record at certain places can play an influence, but you're always trying to find a balance tactically for the conditions you find tomorrow.
"Obviously past form and past bowling it's very important that you look at that because you can't go with what happened two years ago or a year ago.
"That's part of the skill of being a selector, weigh up all those conundrums and try and come up with the right answer at the end.
"You try to be as loyal as you can to your players who won the Test match, you want to give people a feeling of confidence in the side and get a good run.
"But on the other hand you pick a side which you think is going to win that game. And I think sometimes you have to make tough decisions, every situation is different."
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- Stuart Broad
- Tim Bresnan
- Graham Onions