Midfielder Josh McEachran has not played in the competition to date under the terms of his loan agreement with the Blues, while Kieron Dyer and Sammy Ameobi are cup-tied.
Dyer played for former club QPR in a 1-1 third-round draw with West Brom, while Ameobi, who on Monday joined Boro on loan from neighbours Newcastle for the rest of the season, started the Magpies' 2-0 defeat at npower Championship Brighton at the same stage of the competition.
Mowbray will also be without striker Lukas Jutkiewicz (ankle) and central defender Jonathan Woodgate (calf), although the latter has a chance of returning for the league clash with league leaders Cardiff at the weekend.
In addition, Stuart Parnaby (hamstring tear), Justin Hoyte (hip) and Julio Arca (toe) remain on the sidelines.
- Sports & Recreation
- Sammy Ameobi
- Kieron Dyer
- West Brom