The 24-year-old shot to prominence while with Dundee United, for whom he scored 19 times three seasons ago, before securing his big move south of the border.
Things have not quite worked out for him at Rovers, though, and he found himself marginalised even after their relegation to the Championship last season.
Goodwillie rejoined Dundee United on loan at the start of this campaign yet he was unable to rekindle the form of his last spell and scored just six times in 22 appearances.
The striker's representatives told Press Association Sport that Goodwillie was determined to prove himself at Ewood Park but with interest from Aberdeen, St Johnstone and Oldham, another move could be in the pipeline.
"That's a discussion that we and Goody have got to have," Bowyer said.
"Full credit to him, last time he didn't want to be sat around on the bench he wanted to be able to get out and play some games. That was one of his decisions and we supported that."
Goodwillie has 18 months left on his present deal and seemingly moves to the bottom of the pecking order at Rovers behind fellow forwards Jordan Rhodes, Rudy Gestede, DJ Campbell and possibly Leon Best too.
Bowyer was reluctant to confirm the clubs who were sniffing around for another loan move, however.
He added: "His loan's finished with Dundee United now so we're expecting him back in unless somebody else comes in for him. There's been one or two enquiries but nothing more than that.
"I think it would be unfair for me to say which clubs have actually rang up about David until we get a concrete offer from somebody. It's not right to say who it might be or who it might not be."
However, if nothing occurs before Wednesday night's trip to the Etihad Stadium, Goodwillie may feature in a Rovers shirt for the first time since May.
"We just had a discussion and Goody could find himself back in the squad," Bowyer confirmed.
"He's a Blackburn Rovers player. There's been no official bids and, until there is, he's part of our squad again."
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