The defender underwent knee surgery last week and remains out while he continues his recovery. Lee Collins stood in for Langmead during Friday's 1-0 win over Torquay and he is likely to deputise once more.
Striker Clive Platt, who was taken off at half time on Saturday as a precaution, will start up front once again.
Boothroyd believes his side cannot drop points against their promotion rivals.
He told the club's official website: "Cheltenham are a very good, strong side, they beat us 3-2 at Sixfields which shows you their resilience.
"We will go there with real confidence and we've just got to make sure we come away with something.
"A point would be good but three would be brilliant."
- Sports & Recreation
- Clive Platt