The 37-year-old, who scored 80 times for the Pirates between 1996 and 2000, is available to hit the impressive milestone having served his three-game suspension for a red card against Wycombe on New Year's Day.
Cureton is likely to replace Irishman John O'Flynn in the starting line-up after the striker was ruled out for at least a month with a hamstring picked up in the early stages of the midweek draw.
Midfielder Liam Sercombe remains sidelined with an ankle injury while Guillem Bauza will hope to be involved again having made his first start since September at Torquay on Tuesday.
Matt Oakley and Alan Gow in particular helped the Grecians battle back to earn a point at Plainmoor and the experienced duo could return to the starting line-up.
- Sports & Recreation