Karleigh Osborne pulled a hamstring and Dan Shittu suffered a calf injury during the 2-0 win at Charlton a fortnight ago.
Mark Beevers is suspended for collecting 10 yellow cards this season and Paul Robinson remains a long-term absentee with a groin injury.
Boss Kenny Jackett has drafted in free agent and former Colchester defender Tom Bender as cover.
Winger James Henry is also missing with a knee ligament injury, although the Lions hope he will be fit before the end of the season.
Jermaine Easter could start in attack after marking his first appearance since joining on loan from Crystal Palace by scoring with his first touch as a sub at The Valley.
- Sports & Recreation
- Mark Beevers