Left-back Gary Sawyer will miss out after he was stretchered off during Saturday's 2-1 defeat by Hartlepool, with Orient waiting to find out the severity of his knee injury, and striker Charlie MacDonald is cup-tied.
Boss Russell Slade will check on winger Dean Cox after he sat out at the weekend with a thigh problem, while forward Kevin Lisbie is still missing with a hamstring injury.
Slade could hand a full debut to utility man Romain Vincelot, who has made two substitute appearances since joining from Brighton earlier this month.
Nathan Clarke, Leon McSweeney, Jimmy Smith and Anthony Griffith are pushing for recalls as the O's attempt to overturn a 1-0 deficit from the first leg.
- Sports & Recreation
- Gary Sawyer
- Kevin Lisbie