Veteran Drummond, 38, sustained the injury during the 1-1 draw against Dagenham on Saturday and missed Tuesday night's 5-1 defeat at Accrington.
"It looks like he (Drummond) will miss the rest of the season, he's fractured his toe," Shrimps boss Jim Bentley told The Visitor after the heavy loss to Stanley.
"Parrish luckily has only got a partial tear of his cruciate which is two to four weeks, but we missed them both.
"Fleming's arguably been our best player this year and he'll come back in on Saturday (against Northampton) without a doubt. b(And Beeley's out too. Whoever goes out on Saturday is going to have to put this right because I'm looking for a reaction.
"I'm sick of saying that too after what happened in the Plymouth game but we'll ask questions again because we need a response."
- Sports & Recreation
- Disease & Medical Conditions
- Andy Parrish
- Shaun Beeley
- Andy Fleming