Debuchy sustained a thigh injury during Newcastle United's 2-1 Premier League defeat at Wigan Athletic at the weekend.
"He's out for both games. I called up Rod Fanni who will join us in the evening," Deschamps said.
Marseille full-back Fanni has five caps for France.
Les Bleus, who are second in their World Cup qualifying Group I, take on Georgia and leaders Spain at the Stade de France on Friday and next Tuesday respectively.
Goalkeepers: Mickael Landreau (Bastia), Hugo Lloris (Tottenham Hotspur), Steve Mandanda (Olympique Marseille)
Defenders: Gael Clichy (Manchester City), Patrice Evra (Manchester United), Christophe Jallet (Paris St Germain), Laurent Koscielny (Arsenal), Mamadou Sakho (Paris St Germain), Raphael Varane (Real Madrid), Mapou Yanga-M'Biwa (Newcastle United), Rod Fanni (Olympique Marseille)
Midfielders: Yohan Cabaye (Newcastle United), Maxime Gonalons (Olympique Lyon), Blaise Matuidi (Paris St Germain), Dimitri Payet (Lille), Paul Pogba (Juventus), Moussa Sissoko (Newcastle United), Mathieu Valbuena (Olympique Marseille)
Forwards: Karim Benzema (Real Madrid), Olivier Giroud (Arsenal), Bafetimbi Gomis (Olympique Lyon), Jeremy Menez (Paris St Germain), Loic Remy (Queens Park Rangers), Franck Ribery (Bayern Munich)
- Sports & Recreation
- Rod Fanni
- Newcastle United
- Olympique Marseille