The Grecians have won just one of their last eight matches at St James Park but Tisdale's side are just two points outside the play-offs thanks to seven away wins, matched only by top two Gillingham and Port Vale.
Following the 3-1 defeat to Oxford Tisdale said: "Games at home are different to games away in the way that the opposition play and we have to find a way that fits and works for us."
Tisdale could welcome back midfielder Tommy Doherty, who has been out with a hamstring injury for the past month, as he searches for a solution.
Striker Jamie Reid impressed as a substitute on his Football League debut and is pushing for inclusion while Kevin Amankwaah, Arron Davies and Jimmy Keohane are further options.
- Sports & Recreation