Tigers boss Steve Bruce feared Hobbs had been ruled out for the rest of the season after sustaining an ankle injury in the recent home defeat to Watford, but he has responded well to treatment and is hoping to feature.
Fryatt has been sidelined for eight months with an Achilles injury and having returned to full training is expected to play a cameo role.
The return of Hobbs and Fryatt would be a timely boost for Bruce, who will be without Egyptian striker Gedo, who aggravated a foot injury in training, and defender Alex Bruce, who appears to have played his last game of the season after rupturing his Achilles during last weekend's win over Middlesbrough.
The Tigers, three points clear of nearest rivals Watford in the race for the second automatic promotion spot, are chasing a third straight away win.
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