Turf Moor, where the Clarets have not lost in their last 13 contests, has been a fortress for Sean Dyche's men in the League Cup too, with the previous 10 ties at their East Lancashire home all having been won by the hosts.
Those statistics, coupled with the fact Burnley have equalled their best-ever start to a season, suggests the Hammers' trip will be all the more daunting just two days after they travelled to south Wales to face Swansea.
It is therefore no surprise that Burnley's leading goalscorer Ings is so insistent the Barclays Premier League club will become the 11th straight scalp on Tuesday night.
"I'm sure we're going to beat them," said the 21-year-old.
"I'm really confident about that game. I'm sure with the confidence we've got at the moment we can turn anyone over. The crowd have been great getting behind us and it seems to be getting louder and louder."
The form of Ings and his fellow striker Sam Vokes, who have scored 21 goals between them, is a large reason for the Clarets' success this season and their partnership could prove pivotal once more, particularly given the limited options that West Ham boss Sam Allardyce has in his own attacking department.
However, even if Allardyce does again deploy his much-talked-about 4-6-0 formation, Ings has inside knowledge of the man likely to pose the biggest threat to his team-mates.
Ravel Morrison was in the England Under-21s squad when Ings was called up to Gareth Southgate's set-up earlier this month and the former Manchester United prodigy certainly caught the eye.
"He's got all the ability in the world, he's a great player," said Ings.
"On the ball he's incredible. He was really good in training, he scored some ridiculous goals as well, he's a good player."
When asked how he will advise his team-mates to stop Morrison, Ings added: "Keep it away from him!
"Hopefully we'll get me and Vokesy on the ball and get some goals."
Saturday's 2-0 win over QPR was seen as a statement for Burnley's play-off aspirations although a raft of injuries in midfield have left them looking short in midfield.
David Jones will serve a one-match ban against West Ham after picking up five yellow cards and injured duo Scott Arfield, who missed out against Rangers, and Dean Marney are both rated 50-50.
While Ings acknowledges several injuries could disrupt their impressive momentum, he is upbeat about a run of form which has seen the Clarets win eight on the spin.
"We're going out there and running over teams," he added in the Lancashire Telegraph.
"We're fit; we've got the ability on the pitch. People will say our only problem is the depth of our squad but I'm sure if we keep all the lads fit then we've got every chance."
- Sports & Recreation