The Irishman, selected ahead of summer signing Razvan Rat, was part of a Hammers back four which kept a clean sheet in the 2-0 defeat of the newly-promoted Welshmen.
Now O'Brien is targeting a repeat showing of the win at St James' Park last term, when he set-up the winner for former Newcastle captain Kevin Nolan.
"I was delighted to get the nod (against Cardiff)," O'Brien told West Ham TV.
"Roland is a smashing player and George McCartney is on his way back as well, so hopefully I can stay there or whoever comes in can play well."
"It (Newcastle) is a very hard place to go, but we'd take what happened last season and if Kev could score again that would be great.
"We're going up there setting off to keep a clean sheet and we'll see how we go from there.
"That will be aim and hopefully we can defend the way we did against Cardiff and get a result."
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