Right-back Omozusi has rejoined the O's on a contract until the end of the season, having been released from prison in the autumn.
Manager Russell Slade is still without centre-half Nathan Clarke (ankle) and striker Kevin Lisbie (hamstring).
Slade made five changes to the team which took Hull to extra time in the FA Cup last Tuesday when they travelled to Doncaster at the weekend.
His patched-up side went down 2-0 so further changes could be made with the likes of Lee Cook, Martin Rowlands and David Mooney pushing for starts.
Defender Mathieu Baudry missed out on Saturday with a knock and will be checked over.
- Sports & Recreation