Ward, who netted his 12th goal of an injury-interrupted season during the 3-0 home win over Bristol City last Friday, missed Monday's victory over Leeds with a tight hamstring while Bryson was forced off at Elland Road after 34 minutes due to a groin problem.
Rams boss Nigel Clough will make a late decision on both players.
He said: "Hopefully, they will be okay. We will leave it as late as possible with them. We'll leave it until Friday, even Saturday morning to see how they are. They are important for us and we want them out there if possible."
Craig Forsyth's loan from Watford has been extended. His initial deal expired after the Leeds game but the midfielder will now remain at Pride Park for the remainder of the season.
The 24-year-old will probably continue to deputise at left-back if Gareth Roberts misses a fourth match with his calf problem.
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