Rovers recorded their first league win in seven outings against Crewe on Boxing Day to retain their place in the top two.
On-loan West Brom defender Donervon Daniels was handed a first Tranmere start at centre-back for the 2-1 triumph at the expense of benched veteran Ian Goodison.
Skipper James Wallace is back in light training but will not return from his medial knee ligament injury until the new year.
Defender Mark McChrystal is back at Prenton Park after his loan spell with the Iron expired.
Forward Jean-Louis Akpa Akpro (broken metatarsal) and winger Abdulai Bell-Baggie (lateral knee ligament) remain sidelined.
Moore's men triumphed 3-1 at Glanford Park in October in the reserve fixture.
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