O'Grady has missed the last four games due to a calf strain, but returned to full training this week and is hoping to add to his seven goals for the season in Mellon's first home game since David Flitcroft was sacked.
O'Grady could partner Marcus Tudgay up front for the first time since the latter's recent arrival on loan from Nottingham Forest.
Mellon, who guided the Reds to victory at Brighton before last weekend's narrow defeat at Burnley, has no new selection problems, while striker Marcus Pedersen, midfielders David Fox and Stephen Dawson, plus defender Bobby Hassell are all in contention.
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- David Flitcroft
- Marcus Tudgay