The Shrimpers went ahead just before the break when Barry Corr firing in from close range.
But Pools levelled in the 59th minute, with Walker on target with a well-struck volley.
However, they took the lead in the 43rd minute when Corr impressively converted a low left-wing cross from Kevan Hurst with a near flick.
Straker had a well-struck shot well saved by Scott Flinders at the start of the second half before Hartlepool equalised with Walker collecting a loose attempted clearance from Michael Timlin and netted with a volley from 20 yards.
Southend pushed hard after being pegged back and almost went back in front when Hurst had a shot blocked on the line by full-back Darren Holden.
- Sports & Recreation
- Anthony Straker
- Kevan Hurst