"I think you have first to realise that all four (English) teams came out of the group stage. That means the level is there," Wenger said on Thursday.
"After only one game, you cannot judge a general trend."
England are rated second to Spain in UEFA's rankings but are in danger of having no team in the quarter-finals of the Champions League for the second consecutive season.
Last season only Arsenal and Manchester United, who hold the record for the most Champions League quarter-finals with Bayern and Barcelona, reached the knockout rounds.
"Man City played with 10 men, Arsenal played with 10 men, Man City played against Barcelona, Arsenal played against Bayern Munich, who are world champions," Wenger told reporters.
"Of course you know that with 10 men it will be a difficult game. After that the other two teams are still in positions, Man United and Chelsea, where they can turn the results around.
"Let's wait until the end of the second game before talking about a trend of strength or weakness."
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