Byram made his first start since April against Burnley on Saturday following a hip injury but was feeling sore when he was withdrawn after an hour, and Peltier missed the 2-1 defeat with a groin problem.
But a third full-back, Stephen Warnock, will be available after sitting out at the weekend through suspension.
Striker Matt Smith is in line for another start in the cup after climbing off the bench to scores Leeds' consolation goal against the Clarets.
- Sports & Recreation
- Stephen Warnock