Heavy fog not only restricted visibility but also affected track conditions, meaning the first half hour was an affective write-off.
Only three men ventured out during that time, with wildcard entrant Steve Rapp at least providing the fans with some cheer as his Kawasaki-powered Attack Performance CRT bike vied with Aleix Espargaro (Aspar) and James Ellison (Paul Bird) for top spot.
When Rapp got down to a 1m27.486s, faster than he went on Friday, it finally served notice to the rest of the pitlane that track conditions were good enough to interest them.
Breaking away from impromptu pitlane interviews and meetings, they slowly filtered out, with Yamaha's Ben Spies leading the way. The American eventually wound up second, behind Lorenzo.
He could not really hold a candle to the Spaniard however, with Lorenzo underlining his dominance by setting a 1m21.445s as the chequered flag waved.
Ducati took third and fifth in the hands of Nicky Hayden and Valentino Rossi, although such form was tempered by Casey Stoner and Dani Pedrosa's decision not to go out at all. The Spaniard in particular has been in fine form, topping both Friday sessions.
Tech 3 Yamaha's Andrea Dovizioso shared a similar sentiment until the final minutes, when he escaped to set the 20th fastest time.
Team-mate Cal Cruthclow meanwhile ended fourth, ahead of Rossi, LCR Honda's Stefan Bradl and Gresini's Alvaro Bautista.
With caution prevailing there was only one accident, Ivan Silva losing the front of his bike at the Corkscrew in the final minute.