Parrott, the 1991 champion, was thrashed 5-0 by Patrick Wallace at the English Institute of Sport to see his hopes of making it into the main draw evaporate.
Wallace then made it into the third qualifying round with a 5-2 win over Joe Delaney.
Phillip Minchin and David Gray were among those who also fell at the opening hurdle.
Igor Figueiredo 10-5 Jamie O'Neill
Patrick Wallace 5-2 Joe Delaney
David Singh 5-1 Barry Stark
Jamie O'Neill 5-0 Stephen Ormerod
Justin Astley 5-2 Del Smith
Patrick Wallace 5-0 John Parrott
Joe Delaney 5-4 Stephen Rowlings
Barry Stark 5-3 Philip Minchin
David Singh 5-0 Ali Bassiri
Jamie O'Neill 5-4 David Gray
Justin Astley 5-0 Les Dodd